Management of neural tube defects

Mirsad Hodžić, Hasan Altumbabić, Mirza Moranjkić, Zlatko Ercegović, Selma Jakupović


Objective - The aim of this study was to present our experience in managed neural tube defect in a consecutive series of 18 patients.

Material and methods - In the period between October 2003 and October 2007 eighteen patients with neural tube defect (NTD) were operated at Department of neurosurgery of University clinical center Tuzla. Each patient with suspected NTD was evaluated by pediatricians, radiologists and neurosurgeons with clinical findings and ultrasound investigation, computerized tomography and/or magnetic resonance imaging scans of the spine and head.

Results - The neurosurgical data of 18 patients with NTD who were admitted and treated at our department over the four year period were studied retrospectively. The average age at the time of presentation was 15.7 months, ranging from 1 day to 8 years. Spinal NTD was noticed in 13 (72.2%) patients and cranial in 5 (27.8%) patients. Surgery was performed on emergency basis immediately upon birth for CSF leakage in five patients (38,5%) with spinal dysraphism. No postoperative cerebrospinal fluid leakage was noticed and there was no mortality.

Conclusion - Patients born with neural tube defect need an interdisciplinary team of specialists to oversee their developmental progress. Once born, a child with NTD must be operated in order to avoid fluid infection.


Neural tube defect; Management; Outcome

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