Newborn screening programm for congenital hypothyroidism in Montenegro

Mira Samardžić, Najdana Gligorović-Barhanović, Nataša Popović, Milena Popović-Samardžić

Abstract


Objective – The aim of this study was to assess the prevalence of congenital hypothyroidism (CH) over the last 5 years and analyze and summarize the status of newborn screening in Montenegro.

Materials and methods – This is a population-based retrospective study. Blood samples were collected from the heels of newborns 48 – 96 hours after birth and thyroid-stimulating hormone (TSH) was determined. The cut off value in our laboratory was 10 mIU/l in whole blood. Dissociation-enhanced lanthanide fluorescent immunoassay (DELFIA) was used for detection.

Results – Over the period January 2008 – December 2012, a total of 40,758 newborns were screened and 17 cases were confirmed as CH - both transient and permanent. The program covered all live born infants (100%). Recall rate was 0.97 – 1.36%. Mean age of starting treatment was 21.4±6.4 days.

Conclusion – During the period of analysis in our study, 17 cases of CH were detected. The overall prevalence of CH was 1 in 2397 live births. This is the first report on newborn screening for congenital hypothyroidism in Montenegro.


Keywords


Congenital hypothyroidism; Neonatal screening; Montenegro.

Full Text:

PDF


DOI: https://doi.org/10.5457/p2005-114.70

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

The full text of articles published in this journal can be used free of charge for personal and educational purposes while respecting authors and publishers' copyrights. For commercial purposes no part of this journal may be reproduced without the written permission of the publisher.